Testosterone Therapy for the Treatment of Non Alcoholic Fatty Liver Disease

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in Australia, damaging the liver from inflammation due to excessive fat. It can cause liver failure and liver cancer and currently has no treatment. Low testosterone (T) levels are common in men with NAFLD and may worsen the disease. It is plausible that T therapy could reduce liver fat in NAFLD patients. I plan to run a clinical trial investigating the effects of T therapy in men with NAFLD and low T levels.

Related publications (1)

Testosterone is lower in men with non-alcoholic fatty liver disease and alcohol-related cirrhosis and is associated with adverse clinical outcomes

R Apostolov, D Wong, E Low, K Vaz, J Spurio, T Worland, D Liu, RK Chan, P Gow, M Grossmann, M Sinclair

2023-01-01

Background/aims: Low serum testosterone is common in cirrhotic men, but the impact of disease aetiology remains uncertain. This st..